HT2A Receptor Binding is Increased in Borderline ersonality Disorder
نویسندگان
چکیده
ackground: Postmortem studies in suicide victims demonstrate an increase in the number of post-synaptic 5-HT2A receptor binding sites in entral lateral and orbital frontal cortex. Diminished metabolic responses to serotonergic activation are noted in these areas in impulsive subjects ith borderline personality disorder (BPD), a group at high risk for suicidal behaviors. We examined 5HT2A receptor binding potential (BP) in mpulsive subjects with BPD, with positron emission tomography neuroimaging with [F] altanserin.
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